Key Investor Information for Investors in the United Kingdom This document provides you with key investor information about this fund. It is not marketing material. The information is required by law to help you understand the nature and the risks of investing in this fund. You are advised to read it so you can make an informed decision about whether to invest. Xtrackers MSCI Genomic Healthcare Innovation UCITS ETF Share class: 1C, ISIN: IE000KD0BZ68, Security code: DBX0R2, Currency: USD a sub-fund of Xtrackers (IE) plc. The management company is DWS Investment S.A., a member of the DWS Group. Objectives and investment policy The fund is passively managed. INVESTMENT OBJECTIVE: The the companies are reinvested in the shares after tax. The index is aim is for your investment to track the performance before fees and reviewed semi-annually and rebalanced at least quarterly. The expenses of the MSCI ACWI IMI Genomic Innovation Select index is calculated in USD on a daily basis. INVESTMENT POLICY: Screened 100 Index (index). DESCRIPTION OF INDEX: The index To achieve the aim, the fund will attempt to replicate the index, is based on the MSCI ACWI IMI Index (Parent Index) and reflects before fees and expenses, by buying all or a substantial number of the performance of large, medium, and small-capitalisationthe securities in the index. The fund may employ techniques and companies globally that derive, or are expected to derive,instruments in order to manage risk, reduce costs and improve significant revenues from technological innovation in the genomic results. These techniques and instruments may include the use of healthcare sector. Companies from the Parent Index that pass both financial contracts (derivatives). The fund may also engage in thematic selection criteria and ESG screening criteria are eligible. secured lending of its investments to certain eligible third parties The thematic selection criteria calculates a relevance score for subject to certain ESG criteria to generate additional income to potential constituents by assessing companies’ exposure tooffset the costs of the fund. FURTHER INFORMATION: Certain business activities associated with the theme. Securities must meet information (including the latest share prices of the fund, indicative a certain relevance score threshold to be eligible. ESG CRITERIA: net asset values, full disclosure on the composition of the fund's The ESG screening criteria excludes companies from the Parent portfolio and information on the index constituents) are available on Index which breach certain ESG standards, as disclosed in the your local DWS website or at www.Xtrackers.com. Transaction prospectus and/or supplement. The remaining securities are then costs and taxes, unexpected fund costs and market conditions such ranked by their market capitalisation and the top 100 are selectedas volatility or liquidity issues may affect the ability of the fund to for inclusion. Securities are weighted by a product of their market track the index. The anticipated level of tracking error in normal capitalisation and their relevance score. Each issuer is capped atmarket conditions is 1 per cent. The currency of the fund is USD. 4.5% weight at each rebalance. INDEX REBALANCING, Returns and gains are not distributed but are reinvested in the fund. CALCULATION AND ADMINISTRATION: The index is You may request the redemption of shares generally on a daily administered by MSCI Limited. The index is calculated on a total basis. return net basis, which means that all dividends and distributions by Risk and reward profile Lower risk Higher risk RISK: The value of an investment in shares will depend on a number of factors including, but not limited to, market and Potentially lower reward Potentially higher reward economic conditions, sector, geographical region and political 1 2 3 456 7events. COUNTRY RISK CHINA: The fund is exposed to liquidity, operational, clearing, settlement, market suspension and custody The calculation of the risk and reward profile is based on simulated risks linked to investments in the People’s Republic of China data that cannot be used as a reliable indicator for the future risk (“PRC”) and Stock Connect. The fund may suffer difficulties or profile. This risk indicator is subject to changes; the classification of delays in enforcing its rights in A-shares given the securities the fund may change over time and cannot be guaranteed. Even aregimes in the PRC and Hong Kong are different. The fund and the fund that is classified in the lowest category (category 1) does not depositary cannot ensure that the fund’s ownership of the represent a completely risk-free investment. The fund is classified securities in the PRC or title thereto is assured in all in category 6 because its share price may fluctuate strongly and circumstances. The Board of Directors intends to make relevant the likelihood of both losses and gains may therefore be high. Theprovision on dividend and interest from A-shares if the tax on following risks could be of particular significance for the fund: The dividends is not withheld at source at the time when such income is fund will attempt to replicate the performance of the index less received. Any such provision may be excessive or inadequate. costs, but your investment is not expected to match the Investors may be advantaged or disadvantaged depending on the performanceofthe index precisely. EXCEPTIONALtime they subscribed and/or redeemed their shares. CIRCUMSTANCES RISK: Exceptional circumstances may arise, SUSTAINABILITY RISK: The ESG screening criteria are such as, but not limited to, disruptive market conditions, additional embedded within the index selection process, which seeks to costs/taxes or extremely volatile markets, which may cause theexclude securities issued by companies involved in certain fund's performance to be substantially different from the activities. The investment manager and sub-portfolio manager are performance of the index. CONFLICTS OF INTEREST RISK: DWS not responsible for monitoring the screening process or confirming entities and related companies may act in several roles in relation that all securities which pass the screening process are issued by to the fund such as distributor and management company which companies with adequate ESG standards. The company is solely may involve conflicts of interest. EMERGING MARKETS RISK: relying on the activities conducted by and information provided by The fund is exposed to less economically developed economies the administrator of the index and MSCI ESG Research LLC for the (known as emerging markets) which involve greater risks than well ESG screening. ESG information from third-party data providers developed economies. Political unrest and economic downturn may be incomplete, inaccurate or unavailable. As a result, there is may be more likely and will affect the value of your investment. a risk that the index administrator may incorrectly assess a security Settlement of buy or sell transactions for the fund may be delayedor issuer, resulting in the incorrect inclusion or exclusion of a and there may be uncertainty about the ownership of the fund’ssecurity in the index. DERIVATIVES RISK: The fund may use investments. The custodian may not in certain circumstances bederivatives for investment purposes and to try to manage its liable to the fund for its acts and omissions or those to whom it investments more efficiently. This may not always be successful delegates custody of the fund’s investments. NO GUARANTEE and may result in greater fluctuations in the value of the fund. This RISK: The fund is not guaranteed and your investment is at risk. may negatively affect the value of the fund and your investments. The value of your investment may go down as well as up. SHARESA more detailed description of risks and other general information can be found in the risk section(s) of the prospectus. Charges The charges you pay are used to pay the costs of running the fund, including the costs of marketing and distributing it. These charges reduce the potential growth of your investment. One-off charges taken before or after you invest Secondary market investors (those who buy or sell shares Entry charge Noneon a stock exchange) may be charged certain fees by their Exit charge Nonestock broker. These charges, if any, can be obtained from such stock broker. Authorised participants dealing directly This is the maximum that might be taken out of your money before it is with the fund will pay the transaction costs related to their invested (entry charge) and before the proceeds of your investment are paid subscriptions and redemptions. out (exit charge). The ongoing charges figure is based on expenses for the Charges taken from the fund over a year fiscal year ending 31.12.2024. It may vary from year to Ongoing charges 0.30 %year. It excludes portfolio transaction costs and Charges taken from the fund under certain specific conditions performance fees, if any. Performance fee None Additional information on costs can be found in the cost Securities lending fees 0.00 %section(s) of the prospectus. To the extent the fund undertakes securities lending to generate revenue, the fund will ultimately be allocated 82% of the associated revenue, the securities lending agent, which will be a Deutsche Bank entity, will be allocated 9% and the remaining 9% will be allocated to the DWS entity which monitors such activities, as set out in the sales prospectus and/or supplement, for its own coordination and oversight tasks. As securities lending revenue sharing does not increase the costs of running the fund, this has been excluded from the composition of costs. Past performance aaa Past performance is not a reliable indicator of future performance. All costs and fees that were withdrawn from the 1C share class of Xtrackers MSCI Genomic Healthcare Innovation UCITS ETF were deducted during the calculation. The 1C share class of Xtrackers MSCI Genomic Healthcare Innovation UCITS ETF was launched in 2022. Practical information The depositary is State Street Custodial Services (Ireland) Limited, statement contained in this document that is misleading, inaccurate Ireland. Copies of the prospectus and the periodic reports are or inconsistent with the relevant parts of the sales prospectus. This available free of charge in the language of this document. The fund is a sub-fund of Xtrackers (IE) plc for which the sales documents as well as other information (including the latest share prospectus and the periodic reports are prepared as a whole in prices as well as the indicative net asset values) are available freeaddition to individual supplements per sub-fund. The assets and of charge. The documents are available on your local DWS website liabilities of each sub-fund are segregated by law. As a result, or at www.Xtrackers.com. Information on the current remuneration assets of one sub-fund are not available in the event of claims policy of the management company, including a description of how against or insolvency of another. More share classes may be remuneration and benefits are calculated is published on the available for this fund - please refer to the relevant section of the Internetat https://www.dws.com/footer/Legal-Resources/dws- supplement for further details. You are not permitted to exchange remuneration-policy?setLanguage=en. The information will be sent your shares in this fund for other funds of Xtrackers (IE) plc. This to you in paper form free of charge upon request. Taxation regimes fund is authorised in Ireland and is regulated by the Central Bank applicable to the fund in your jurisdiction may affect your personal of Ireland. DWS Investment S.A. is authorised in Luxembourg and tax situation. Prospective investors should inform themselves of,is regulated by the Commission de Surveillance du Secteur and where appropriate take advice on such taxation regimes. Financier. Xtrackers (IE) plc may be held liable solely on the basis of any This key investor information is accurate as at 12.02.2025. The MSCI indices are the exclusive property of MSCI Inc. and its subsidiaries (MSCI) and may not be reproduced or extracted and used for any other purpose without MSCI’s consent. The fund is not sponsored, endorsed, or promoted by MSCI, and MSCI bears no liability with respect to the fund or any index on which such fund is based. The MSCI indices are provided without any warranties of any kind.