Title: AKR0 PRIIP KID URL Source: https://www.fundslibrary.co.uk/FundsLibrary.DataRetrieval/Documents.aspx?type=packet_fund_unit_doc_priip_kid&docid=cb566960-a529-4402-9c16-800cbfea4ffe&user=66qSNW5HmcOqx6NT2ocpyL+I7wIalFZAPKjdx8/lXoM= Published Time: Tue, 19 May 2026 11:22:43 GMT Number of Pages: 3 Markdown Content: Key Information Document There is no requirement for investors to receive a regulated Key Information Document before buying these shares. As an alternative, this document provides you with key information about this investment product. It is not marketing material. It helps you understand the nature of this product and to help you compare it with other products. Other documents are available to help you understand the potential gains and losses of this product # Product The Biotech Growth Trust PLC ISIN: GB0000385517 Frostrow Capital LLP ('Frostrow') is the alternative investment fund manager of the Company. Frostrow's website is www.frostrow.com and phone number is 0203 0084910. Frostrow is authorised and regulated by the Financial Conduct Authority. Portfolio Management has been delegated to OrbiMed Capital LLC ('Portfolio Manager'), which is registered under the Securities & Exchange Commission ('SEC'). Date of Production: 19/05/2026 # What is this product? The Biotech Growth Trust PLC (the 'Company') is a public limited company whose shares are traded on the main market of the London Stock Exchange ('LSE') and is registered with HMRC as an investment trust. The Company seeks capital appreciation through investment in the worldwide biotechnology industry. In order to achieve its investment objective, the Company invests in a diversified portfolio of shares and related securities in biotechnology companies on a worldwide basis. Performance is measured against the NASDAQ Biotechnology Index (net total return, sterling adjusted) (the 'Benchmark'). The Company does not have a fixed life although shareholders consider and vote on the continuation of the Company every five years (the next such vote will be held in 2028). The intended retail investors are those with a long-term (at least five years) investment horizon, the ability to bear capital losses and at least basic market knowledge and experience. The Company can increase its exposure to investments via the use of an overdraft facility and derivatives. This could potentially magnify any gains or losses made by the Company. Shares in the Company are bought and sold on the LSE. The price you pay or receive, like other listed shares, is determined by supply and demand and may be at a discount or premium to the underlying net asset value of the Company. At any given time, the price you pay for a share will normally be higher than the price you could sell it. # What are the risks and what could I get in return? The summary risk indicator (SRI) is a guide to the level of risk of the Company compared to other products. It shows how likely it is that the Company will lose money because of movements in the markets. 1 2 3 4 5 6 7 Lower risk Higher risk The SRI only reflects the historic share price volatility of the Company's shares. It excludes other risks inherent in the Company, including those related to the collateral arrangements on the Company's borrowings and its use of derivatives, and therefore understates the risk to investors. Please refer to the Company's Annual Report at www.biotechgt.com which should be read to ensure a full understanding of the risks involved in investing in the Company. An investor should not make a decision to invest in the Company solely on the basis of this Key Information Document ('KID'). The SRI assumes you hold your shares in the Company for at least five years. It rates the potential losses from future performance at a high level, and poor market conditions will impact the amount you could get back. Any return you receive depends on future market performance and is uncertain. This product does not include any protection from future market performance so you could lose some or all of your investment. # ! We have classified the Company as 5 out of 7, which is a medium high risk class. Page 1 of 3 Investment performance information The Company’s portfolio is exposed to fluctuations in market prices (broad market measures, individual security prices, and foreign exchange rates) in the biotechnology sector and the regions in which it invests. Global, regional, political and macroeconomic events may have an impact on the Company’s performance by causing exchange rate and market price volatility, changes in tax or regulatory environments and/or a reduced investment universe. The biotechnology sector is expected to be more volatile than the wider market. It is affected by certain political and regulatory factors e.g. regulatory drug approvals and drug pricing policy. The portfolio also includes a small number of investments in emerging markets which are generally more volatile than developed markets. The Portfolio Manager can invest up to 10% of the portfolio in unquoted assets, the valuation of which involves a degree of subjectivity. There is a risk that the proceeds received on the disposal of unquoted holdings may prove to be significantly lower than the value at which they were held in the portfolio. The Portfolio Manager’s approach is expected to lead to performance that will deviate from the Benchmark. Over time, the Company aims to outperform the Benchmark but it is expected that the Company’s performance will be more volatile. The Company uses leverage (through gearing) which will amplify the gains or losses of the portfolio. Please refer to the Company's Annual Report at www.biotechgt.com which should be read to ensure a fuller understanding of the factors that may affect future returns. An investor should not make a decision to invest in the Company solely on the basis of this Key Information Document ('KID'). What could affect my return positively? An increase in market prices (generally, or because of the good fundamental performance of the companies held in the portfolio); an increase in the level of gearing during a rising market; a reduction in the discount of the share price to the NAV per share; favourable exchange rate movements (because the majority of the Company’s investments are denominated in currencies other than sterling, if sterling depreciates, this would broadly be expected to have a positive impact on returns). What could affect my return negatively? A fall in market prices (generally, or because of the poor fundamental performance of the companies held in the portfolio); a reduction in the level of gearing in a falling market; an increase in the discount of the share price to the NAV per share; unfavourable exchange rate movements (because the majority of the Company’s investments are denominated in currencies other than sterling, if sterling appreciates, this would broadly be expected to have a negative impact on returns). If a shareholder decides to sell their shares under severely adverse market conditions, they may get back less than the amount initially invested. # What happens if the Company is unable to pay out? The Company is not required to make any payment to you in respect of your investment. If the Company was liquidated, you would be entitled to receive a distribution equal to your share of the Company’s assets, if any are remaining after payment of all of its creditors. As a shareholder you would not be able to make a claim to the Financial Services Compensation Scheme, or other compensation or guarantee scheme, in the event that the Company is unable to pay out. If you invest in the Company, you should be prepared to assume the risk that you could lose some or all of your investment. # What are the costs? The table shows the amounts that are taken from your investment to cover different types of costs. These amounts depend on how much you invest, how long you hold the shares and how well the Company does. The amounts shown here are illustrations based on an example investment amount of £10,000 and different possible investment periods. The person selling you or advising you about the Company' shares may charge you other costs. If so, this person will provide you with information about these costs, and show you the impact that all costs will have on your investment over time. Investment £10,000 Scenarios If you cash in after 1 year If you cash in after 3 years If you cash in at 5 years Total costs £0 £0 £0 Impact on return (RIY) per year 0.00% 0.00% 0.00% > Page 2 of 3 # What are the costs? (continued) The table below shows the impact each year of the different types of costs on the investment return you might get at the end of the recommended holding period and the meaning of the different cost categories. This table shows the impact on return per year One-off costs Entry costs N/A There are no direct entry costs associated with the Company. Exit costs N/A There are no direct exit costs associated with the Company. Ongoing costs Portfolio transaction costs 0.00% The costs of buying and selling underlying investments are incurred by the Company. You do not pay the Company nor the Portfolio Manager for these costs. Other ongoing costs 0.00% The costs relating to portfolio management and other expenses involved in running the Company are paid for by the Company. You do not pay the Company, the Portfolio Manager or other service providers fees. For further information on the costs paid by the Company see the Other Relevant Information section below. Incidental costs Performance fees 0.00% Performance fee costs are incurred by the Company. You do not pay the Company nor the Portfolio Manager a performance fee. Carried interests N/A n/a # How long should I hold it and can I take money out early? Recommended holding period: 5 years The Company's shares have no required minimum holding period but are designed for long-term investment; you should be prepared to stay invested for at least 5 years. This period is deemed appropriate due to the long-term investment horizon taken by the Portfolio Manager. Investors can sell their shares at any time when the LSE is open, either directly or via their advisor or distributor. # How can I complain? As a shareholder you do not have the right to complain to the Financial Ombudsman Service ('FOS') about the management of the Company. Complaints about the Company or the Key Information Document can be made via the Contact section of the Company's website, www.biotechgt.com, by emailing info@frostrow.com or by writing to the Company at 25 Southampton Buildings, London, WC2A 1AL. # Other relevant information This KID should be considered only in conjunction with the Annual Report, the Half Year Report and the Investor Disclosure Document which are available on the Company's website, www.biotechgt.com, along with other information about the Company. These provide further details on the Company's principal risks, including the collateral arrangements. Operating expenses As a listed company, the Company incurs operating expenses, for example, arising in relation to the management of the portfolio. Operating costs are disclosed in the Company’s audited Income Statement within its Annual Report and as an Ongoing Charges Figure ('OCF'). The OCF is calculated annually as a percentage of the average net assets and provides an indication of the underlying day ‐to ‐day running costs of the Company calculated in accordance with guidance from the Association of Investment Companies. The Company’s OCF as disclosed in the latest Annual Report was 1.2%. Further information on the calculation of the OCF, as well as costs more generally, are set out in the Annual Report. For the avoidance of doubt, the OCF is not an additional cost paid by shareholders to the Company. The Company’s published net asset value is net of all costs/fees incurred by the Company or within the underlying investment portfolio. Depending on how you buy these shares you may incur other costs, including broker commission, platform fees and Stamp Duty. The person selling you or advising you about the Company's shares will provide you with additional information about these.